Pfizer’s coronavirus vaccine should be safe for most Americans, but 5 groups may want to wait for more data before getting shots

margaret keenan coronavirus vaccine
Margaret Keenan was the first person to be given the Pfizer coronavirus vaccine outside clinical trials. Getty

US vaccine regulators on Friday authorized the nation’s first coronavirus shot for emergency use.

The Food and Drug Administration has determined that the benefits of Pfizer’s coronavirus vaccine outweigh the known and potential risks to the public, based on data from clinical trials.

Most trial participants reported temporary side effects after being vaccinated, including fatigue, headaches, and pain at the injection site. People under 55 reported more side effects overall, but few participants had severe fatigue or headaches that stopped them from performing normal activities. Serious adverse events were reported in only 0.6% of vaccine recipients.

These results were consistent across genders, age groups, ethnic and racial groups, and people with preexisting medical problems. But several populations were excluded from the trials – meaning it’s still unclear whether the vaccine is safe for

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